Capillary Electrophoresis Method Development

If you use capillary electrophoresis (CE) in your work and want a better understanding of the technique, or want to start with CE method development and want to be well prepared, this course is for you. The course is designed for analytical scientists and technicians who use CE in their regular job, but also lab managers who need to support and review CE work might find it useful. The course will also appeal to the experienced scientist who wants a deeper understanding on the development of robust methods and Quality by Design in CE. Some basic experience is beneficial for better understanding and this course builds on to the course “Introduction to Capillary Electrophoresis”.

“Capillary Electrophoresis Method Development” explains the fundamentals of developing robust, precise and sensitive CE methods from the ground up. The course comprises:

  • The basic principles of capillary electrophoresis
  • Ten different modes of CE, including CZE, CGE, cIEF and chiral CE
  • Method Development Plan and starting points
  • Generic and platform methods
  • Instrumental parameters
  • The electrophoresis solution and buffers
  • Additives to the electrophoresis solution
  • Different modes of detection and their effects on method development
  • Method optimization
  • Quality by Design and Design of Experiments
  • Robustness, system suitability and method transfer
  • Tips for successful implementation of CE in your lab