LC-MS/MS for Chromatographers

$249.00

With the introduction of the mass spectrometer (MS) as a practical detector for a high-performance liquid chromatograph (LC or HPLC) in the early 1990s, LC-MS began to be used for routine applications. One form of LC-MS uses a tandem MS (LC-MS/MS), that has become the go-to instrument for quantitative analysis of drugs in biological matrices in the pharmaceutical laboratory. As they have become more widely used and understood, LC-MS and LC-MS/MS have found their way into environmental applications, synthetic chemistry, protein analysis,
and many other areas. LC-MS/MS has moved from a technique available only to skilled experts in both HPLC and MS to a routine tool usable much as any other HPLC detector.

You will find that this introductory course in LC-MS/MS will give you a good foundation of understanding the technique and how to use it in your daily work. We start out with an overview of different MS techniques, and focus in the majority of the course on the quadrupole mass spectrometer. You will learn how MS works, how ions are produced and fragmented. Sections focus on qualitative, as well as quantitative analysis. Each part of the process, calibration, tuning, sample preparation, HPLC method development, and MS method development are covered. Many tricks and techniques of practical use are presented.

Here’s what the course covers:

  • MS operation, including the operation of the most popular LC-MS interfaces
  • How a quadrupole mass filter works
  • MS calibration and optimization
  • Ion production, fragmentation, and detection
  • Operation in MS, MS/MS, and MS/MS/MS modes
  • Structure determination by product ion analysis
  • Quantitative analysis
  • Sample preparation
  • Method development
  • Validation
  • Techniques to get the most from your LC-MS

User licence:

  • Unlimited individual course access for a 12-month (365-day) period
  • ‘Certificate of Completion’ once all modules of a course have been completed and all quiz questions answered correctly (don’t worry, you can attempt the questions as many times as you like)
  • Tailor-made pricing or site licences** are also available (see below for further information)

FAQ
Check out our FAQ to answer commonly asked questions: https://www.analytical-training-solutions.com/about/

PAYMENT
Online payment for the course is via credit card (Stripe). Alternatively, if you would like to be invoiced directly, please contact us: https://www.analytical-training-solutions.com/contact/

TAILOR-MADE PRICING
We offer tailor-made pricing to individual users who are interested to access up to three multiple courses, please contact us: https://www.analytical-training-solutions.com/contact/

**SITE LICENCE PRICING
To find out more visit our course library: https://www.analytical-training-solutions.com/course-library/

  • One Individual Course – USD975/year
  • Two Individual Courses – USD1,380/year
  • All GC Courses – USD1,500/year
    (Introduction to GC, Intermediate GC, GC-MS for Operators & Developers)
  • All LC Courses – USD2,000/year
    (Fundamentals of HPLC, HPLC & UHPLC Troubleshooting, Advanced HPLC Method Development, LC-MS/MS for Chromatographers, HPLC for Biopharmaceuticals, Principles of HPLC Validation)
  • All LC and GC Courses – USD3,000/year

COURSE ACCESS

  • Instant access: users who sign up for an individual course and pay with a credit card via our shop, will get immediate course access.
  • Manual account set-up: those who sign up for multiple individual courses, site licences, the ‘Interpretation of Mass Spectra’ course or those individual users who asked to be billed directly, will be contacted via email to help set up your course access.

ABOUT US
Analytical Training Solutions, brought to you by Separation Science (www.sepscience.com), is the leading global portal for fundamentals, best practice, troubleshooting and method development training for chromatographic and mass spectrometric techniques. Comprehensive, self-paced online courses and validated learning provides a unique educational resource for analytical chemists. Currently, we offer HPLC training, LC-MS training, GC training and GC-MS training.